MP2PRT-MNG: Identifying Novel Molecular Markers of Response to Radiotherapy in Meningiomas Using Samples from the RTOG-0539
phs003707.v2.p1No linked publication
Overview
- Modality
- DNA methylation (array)Bulk RNA-seqWES
- Sample count
- 350
- Patient count
- 100
- Institution
- Center for Cancer Research, National Cancer Institute, National Institutes of Health
- Corresponding author
- Kenneth Aldape
- Platform
- Illumina methylation array (raw .IDAT files confirmed via dbGaP manifest); RNA-seq and WES sequencing platform not specified in the public dbGaP metadata reviewed
- Access type
- controlled
- Tissue preservation
- Not reported
- WHO edition
- 2007
Cohort detail
- Grade breakdown
- G1: 145 G2: 105 G3: 39
- Sex distribution
- 35 male, 65 female (n=100 subjects)
- Age distribution
- n=350 samples, mean 56 years, median 57, range 18->89 (COLLECTION_AGE field, includes both tumor and blood samples)
- Anatomic location
- 289 of 350 samples from Brain (tumor tissue, PRIMARY_TUMOR_LOCATION='Brain' for all), 61 from Blood (germline control) -- no finer-grained anatomic location reported
- Brain invasion
- Not reported
- Normal/control tissue
- Blood (germline control) (n=61)
Priority attributes
WHO grade breakdown availableLarge cohort (top quartile)
Publications
No publication linked.
Related datasets
Also related: NCT00895622
Sources
- ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs003707.v2.p1
- ftp.ncbi.nlm.nih.govhttps://ftp.ncbi.nlm.nih.gov/dbgap/studies/phs003707/phs003707.v2.p1/GapExchange_phs003707.v2.p1.xml
- ftp.ncbi.nlm.nih.govhttps://ftp.ncbi.nlm.nih.gov/dbgap/studies/phs003707/phs003707.v2.p1/pheno_variable_summaries/phs003707.v2.pht014787.v2.p1.MP2PRT_MNG_Subject.var_report.xml
- ftp.ncbi.nlm.nih.govhttps://ftp.ncbi.nlm.nih.gov/dbgap/studies/phs003707/phs003707.v2.p1/pheno_variable_summaries/phs003707.v2.pht014789.v2.p1.MP2PRT_MNG_Sample_Attributes.var_report.xml
- clinicaltrials.govhttps://clinicaltrials.gov/study/NCT00895622
- PubMedhttps://pubmed.ncbi.nlm.nih.gov/39169220/
- PubMedhttps://pubmed.ncbi.nlm.nih.gov/42265312/