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NF2 disruption by genomic rearrangments drives a subset of radiation induced meningiomas

GSE83933Agnihotri et al., 2017
Modality
DNA methylation (array)
Sample count
39
Patient count
Not reported
Institution
University of Pittsburgh
Corresponding author
Gelareh Zadeh / Kenneth Aldape
Platform
GPL13534
Access type
open
Tissue preservation
Not reported
WHO edition
Not reported
Ontology
Disease: MONDO:0016642 · Tissue: UBERON:0003547
Grade breakdown
G1: 20 G2: 15 G3: 4
Sex distribution
20 female, 19 male (n=39, extracted from GSM 'gender' field)
Age distribution
Not reported
Anatomic location
Not reported
Brain invasion
Not reported
Normal/control tissue
None
WHO grade breakdown availableRadiation-induced etiologyLinked to other modalitiesPeer-reviewed
  • Agnihotri S, et al. Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas. Nature communications, 2017. PMID 28775249 · DOI

Sources

  • GEO
    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE83933
  • PubMed
    https://pubmed.ncbi.nlm.nih.gov/28775249/