Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade
GSE74385Schmidt et al., 2016
Overview
- Modality
- Expression profiling (microarray)
- Sample count
- 62
- Patient count
- 62
- Institution
- Department of Neurosurgery, Experimental Neurosurgery, Heidelberg University Hospital
- Corresponding author
- Christel Herold-Mende
- Platform
- Illumina HumanHT-12 V4.0 expression beadchip (GPL10558)
- Access type
- open
- Tissue preservation
- Not reported
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- G1: 20 G2: 14 G3: 28
- Sex distribution
- Not reported
- Age distribution
- Not reported
- Anatomic location
- Not reported
- Brain invasion
- Not reported
- Normal/control tissue
- None
Priority attributes
WHO grade breakdown availableLarge cohort (top quartile)Primary vs. recurrent annotatedOutcome/survival dataPeer-reviewed
Publications
- Schmidt M, et al. Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade. Oncotarget, 2016. PMID 26894859 · DOI
- Dunn J, et al. Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma. Cancers, 2020. PMID 33167358 · DOI
Related datasets
Also related: PRJNA300220
Sources
- GEOhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE74385
- PubMedhttps://pubmed.ncbi.nlm.nih.gov/26894859/
- DOIhttps://doi.org/10.18632/oncotarget.7396
- PubMedhttps://pubmed.ncbi.nlm.nih.gov/33167358/
- ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/bioproject/PRJNA300220