wbi@bwh.harvard.edu

Genomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas [RNA-seq]

GSE335175Huq et al., 2026
Modality
Bulk RNA-seq
Sample count
10
Patient count
Not reported
Institution
University of Pittsburgh Medical Center
Corresponding author
Paul A. Gardner
Platform
NextSeq 2000 (GPL30173)
Access type
open
Tissue preservation
ffpe
WHO edition
Not reported
Grade breakdown
G1: 10 G2: 0 G3: 0
Sex distribution
10 female (100%, n=10, extracted from GSM 'sex' field) -- consistent with the cohort being defined by long-term depot medroxyprogesterone acetate (a female contraceptive) exposure.
Age distribution
Not reported
Anatomic location
Not reported
Brain invasion
Not reported
Normal/control tissue
None
Linked to other modalitiesMolecular subtype annotatedPeer-reviewed
  • Huq S, et al. Genomic hallmarks of depot medroxyprogesterone acetate-associated meningiomas. Neuro-oncology, 2026. PMID 42258618 · DOI

Also related: GSE335177

Sources

  • GEO
    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335175
  • PubMed
    https://pubmed.ncbi.nlm.nih.gov/42258618/
  • DOI
    https://doi.org/10.1093/neuonc/noag136