wbi@bwh.harvard.edu

Molecular Characterization of Meningioma

GSE299027No linked publication

Johns Hopkins low-grade meningioma spatial atlas

19 low-grade (WHO I/II) meningiomas profiled with full-transcriptome Visium spatial transcriptomics, cross-classified into the Choudhury/Raleigh methylation groups (Merlin-intact/immune-enriched/hypermitotic). No linked publication as of this session, likely an in-progress or very recently released dataset from the Fan Lab (computational spatial transcriptomics methods group).

Modality
Spatial transcriptomics
Sample count
19
Patient count
Not reported
Institution
Johns Hopkins
Corresponding author
Lyla Atta, Jean Fan
Platform
10x Genomics Visium
Access type
open
Tissue preservation
Not reported
WHO edition
Not reported
Grade breakdown
Not reported
Sex distribution
Not reported
Age distribution
Not reported
Anatomic location
Not reported
Brain invasion
Not reported
Normal/control tissue
None

All 19 samples, each spot plotted at its true tissue position, side by side · 48,388 cells, 100 genes, 19 samples merged.

Spots are plotted at true tissue position per sample, not merged into one shared coordinate space -- the 19 samples are independent tissue sections side by side, not directly overlaid.

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Spatial resolutionMolecular subtype annotated

No publication linked.

Sources

  • GEO
    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299027