STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways [scMulti-omics]
GSE297758Youngblood et al., 2026
Overview
- Modality
- Multiome
- Sample count
- 8
- Patient count
- Not reported
- Institution
- Northwestern University
- Corresponding author
- Amy B Heimberger
- Platform
- Illumina NovaSeq X Plus (GPL34284)
- Access type
- open
- Tissue preservation
- fresh_frozen
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- Not reported
- Sex distribution
- Not reported
- Age distribution
- Not reported
- Anatomic location
- Not reported
- Brain invasion
- Not reported
- Normal/control tissue
- None
Interactive gene-expression viewer
RNA arm only, all 4 patients merged (this record's ATAC arm is not part of this viewer) · 45,488 cells, 150 genes, 4 samples merged.
This record's sample_count is 8 (4 patients x GEX+ATAC), but this viewer covers only the 4 GEX/RNA samples -- the ATAC arm (chromatin accessibility) has no equivalent in this project's gene-expression viewer and was not processed here. Samples merged by raw concatenation, not batch-corrected/integrated (same approach ScPCA documents for its own merged objects).
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Priority attributes
Single-cell resolutionLinked to other modalitiesPeer-reviewed
Publications
- Youngblood MW, et al. STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways. Nature communications, 2026. PMID 41680157 · DOI
Related datasets
Also related: GSE297764