Molecular signatures define BAP1-altered meningioma as a distinct CNS tumor with deregulation of Polycomb repressive complex target genes
GSE284758Sievers et al., 2025
Overview
- Modality
- DNA methylation (array)
- Sample count
- 42
- Patient count
- Not reported
- Institution
- University Hospital Heidelberg, Intitute of Pathology
- Corresponding author
- Philipp Sievers, Felix Sahm
- Platform
- GPL13534, GPL21145, GPL33022
- Access type
- open
- Tissue preservation
- both
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- Not reported
- Sex distribution
- 23 female, 19 male (n=42, extracted from GSM 'Sex' field)
- Age distribution
- n=39 of 42 (range 13-80, median approx. 44; extracted from GSM 'age' field)
- Anatomic location
- Not reported
- Brain invasion
- Not reported
- Normal/control tissue
- None
Priority attributes
Linked to other modalitiesOutcome/survival dataPeer-reviewed
Publications
- Sievers P, et al. Molecular signatures define BAP1-altered meningioma as a distinct CNS tumor with deregulation of Polycomb repressive complex target genes. Neuro-oncology, 2025. PMID 40249111 · DOI