Adjacent (not core)
Single-cell RNA sequencing of patient-derived xenograft meningiomas
GSE239795Choudhury et al., 2024
Overview
- Modality
- scRNA-seq
- Sample count
- 23
- Patient count
- Not applicable (PDX xenograft model, not directly patient-derived tissue samples)
- Institution
- University of California, San Francisco
- Corresponding author
- David R Raleigh
- Platform
- Illumina NovaSeq 6000 (GPL24676)
- Access type
- open
- Tissue preservation
- not_applicable
- WHO edition
- Not applicable (cell line)
Cohort detail
- Grade breakdown
- Not reported
- Sex distribution
- Not applicable
- Age distribution
- Not applicable
- Anatomic location
- Not applicable (PDX xenograft model, mouse-hosted)
- Brain invasion
- Not reported
- Normal/control tissue
- None
Priority attributes
Single-cell resolutionLarge cohort (top quartile)Peer-reviewed
Publications
- Choudhury A, et al. Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy. Cancer Discovery, 2024. PMID 38742767 · DOI
Related datasets
Also related: GSE235998, PRJNA1000978
Sources
- GEOhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE239795
- PubMedhttps://pubmed.ncbi.nlm.nih.gov/38742767/
- ncbi.nlm.nih.govhttps://www.ncbi.nlm.nih.gov/bioproject/PRJNA1000978