Cancer-specific deficiency of SMARCE1, a module-linking subunit, generates a targetable chromatin regulatory dependency in clear cell meningioma
GSE174360St Pierre et al., 2022
Overview
- Modality
- Bulk RNA-seq
- Sample count
- 15
- Patient count
- Not reported
- Institution
- Broad Institute of MIT and Harvard, Harvard Medical School, Dana-Farber Cancer Institute
- Corresponding author
- Cigall Kadoch
- Platform
- Illumina NextSeq 500 (GPL18573)
- Access type
- open
- Tissue preservation
- fresh_frozen
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- Not reported
- Sex distribution
- Not reported
- Age distribution
- Not reported
- Anatomic location
- Not reported
- Brain invasion
- Not reported
- Normal/control tissue
- None
Priority attributes
Molecular subtype annotatedPeer-reviewed
Publications
- St Pierre R, et al. SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma. Nature genetics, 2022. PMID 35681054 · DOI