Adjacent (not core)
Single cell transcriptome sequencing of the developing human embryonic meninges
EGAS50000000980, EGAD50000001434No linked publication
Overview
- Modality
- scRNA-seq
- Sample count
- 24
- Patient count
- Not applicable (13 human embryonic specimens, not patients)
- Institution
- Karolinska Institutet
- Corresponding author
- Sten Linnarsson (Data Access Committee) / David R Raleigh, Roger A. Barker, Oscar Persson, Erik Sundstrom (data producers/collaborators)
- Platform
- Illumina NovaSeq 6000, 10x Genomics Chromium (S4 flow cell, target 100,000 reads/cell)
- Access type
- controlled
- Tissue preservation
- Not reported
- WHO edition
- Not reported
Cohort detail
- Grade breakdown
- Not reported
- Sex distribution
- Not reported (EGA sample-level metadata lists biological_sex as 'unknown' for all 24 samples)
- Age distribution
- 13 human embryos, per-sample post-conceptional week (PCW) values ranging 5.5-13.5 (per EGA sample-level descriptions); the dataset-level description states the range as PCW 5.0-13.0, a minor discrepancy noted here rather than resolved by estimation.
- Anatomic location
- Whole dissected meninges for most embryos (20 of 24 samples, per EGA sample-level 'Meninges of embryo PCW X.X' descriptions); one embryo (subject_id BRC2301, 4 samples) had meninges subdivided by region: forebrain dorsal, forebrain ventral, midbrain/hindbrain dorsal, and midbrain/hindbrain ventral. Note this is fetal developmental anatomy, not the adult tumor-location vocabulary (convexity/skull_base/etc.) in docs/controlled_vocabulary.md, which does not apply to this specimen type.
- Brain invasion
- Not reported
- Normal/control tissue
- None
Priority attributes
Single-cell resolutionLarge cohort (top quartile)
Publications
No publication linked.
Related datasets
Also related: 7d66d871-091f-4602-9f42-85f86d2853e0
Sources
- EGA study pagehttps://ega-archive.org/studies/EGAS50000000980
- EGA dataset pagehttps://ega-archive.org/datasets/EGAD50000001434
- EGA Data Access Committeehttps://ega-archive.org/dacs/EGAC50000000576
- cellxgene.cziscience.comhttps://cellxgene.cziscience.com/collections/7d66d871-091f-4602-9f42-85f86d2853e0